Biomaterials Laboratory

Myocardial Tissue Engineering

Bioengineered scaffolds populated with bone marrow-derived mesenchymal stem cells (MSCs) were developed and used for myocardial tissue regeneration. Also, living cell sheets or spheroids of MSCs were developed and used for intramyocardial injection.

Drug-eluting Stent

Rapidly self-expandable drug-eluting stents made of biodegradable polymers were developed for treating the coronary arterial stenosis.

pH/Temperature Responsive Hydrogels

Novel pH/temperature responsive hydrogels were developed as carriers for oral drug delivery, intra-venous injection or intra-muscular implantation or as substrates for production of living cell sheets or spheroids.

Nanomedicine

Novel self-assembled nanoparticles conjugated with specific ligands were developed and used for targeting liver cancer cells. Also, nanoparticles shelled with chitosan were prepared by a simple ionic-gelation method for oral insulin delivery or transdermal gene delivery.

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